The collaborative teaching of library and department is a library service new mode, which is put forward under the guidance of collaborative teaching theory and the reflection of traditional subject services in university libraries. It has great practical significance for the cultivation of innovative talents and the reform of the teaching mode in the university "double firstclass" construction. Based on embedded teaching mode and the connotation of information literacy education, this paper puts forward the connotation and significance of collaborative teaching in libraries and department, builds the new relationship between university libraries and department, then puts forward new path of collaborative teaching based on institutional coordination, personnel collaboration, strategic collaboration and supporter collaboration.