Innovation is the driving force and source of space development. The maker spirit provides the source of power and intellectual support for the development of space innovation. The development of space innovation is the carrier and practice base of the maker spirit. There is a good coupling relation of coordination and promotion between the two. The article analyzes the coupling relationship and route between the two, finds out the relevant elements, and builds the coupling guarantee mechanism. It have made suggestions for the coordinated, winwin and synchronous development of maker spirit and space innovation development, these will jointly promote the sustainable development of library maker space together.